There’s something about a Meatball Sub Casserole that sets your taste buds tingling with excitement. Imagine tender meatballs nestled in a cozy blanket of rich marinara, gooey cheese bubbling at the edges, and crusty bread that promises to be the perfect vessel for all that deliciousness. It’s not just a dish; it’s an experience that invites you to dig in with both hands and let the flavors do their magic.

Now, picture this: it’s a chilly evening, and you’re gathering around the table with friends or family, laughter filling the air as you lift a spoonful of this glorious casserole. It’s the kind of meal that warms your heart and makes you feel like a culinary rockstar—just without the need for an apron or fancy knife skills. Trust me; this Meatball Sub Casserole is bound to become your new go-to comfort food for game nights, potlucks, or just those days when you need a little extra love.
Why You'll Love This Meatball Sub Casserole
- This incredible Meatball Sub Casserole transforms simple everyday ingredients into restaurant-quality flavors that will blow your mind completely
- Foolproof recipe techniques guarantee perfect results every single time, making even novice cooks feel like professional chefs instantly
- Stunning visual appeal with gorgeous colors and mouthwatering aromas creates the ultimate Instagram-worthy dish for any special occasion
- Endlessly adaptable for different dietary needs while working beautifully for meal prep, date nights, or entertaining large groups effortlessly
One time, I made this casserole for my friend’s birthday party, and let’s just say it was an instant hit! Everyone was raving about it long after dinner ended.
Essential Ingredients
Here’s what you’ll need to make this delicious dish:
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Ground Beef: Aim for 80/20 beef for the perfect balance between flavor and juiciness.
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Italian Seasoning: A must-have blend that elevates the meatballs with aromatic herbs.
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Pasta Sauce: Choose your favorite jarred sauce; it’s all about convenience without sacrificing flavor.
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Shredded Mozzarella Cheese: The more cheese, the better! It melts beautifully and adds creaminess.
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Sub Sandwich Rolls: Look for fresh rolls that can soak up all that saucy goodness without falling apart.
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Parmesan Cheese: A sprinkle on top adds a delightful nuttiness and golden crust.
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Fresh Basil (Optional): Use it as a garnish to add freshness and color right before serving.
The full ingredients list, including measurements, is provided in the recipe card directly below.

How to Make Meatball Sub Casserole
Preheat your oven to 375°F (190°C). Grab a 9×13-inch baking dish and lightly grease it with nonstick spray to ensure easy cleanup later.
Mixing Meatballs: In a bowl, combine ground beef with Italian seasoning, breadcrumbs, egg, salt, and pepper. Get in there with your hands—it’s messy but oh-so-satisfying!
Forming Meatballs: Roll the mixture into golf ball-sized meatballs. Place them on a baking sheet lined with parchment paper. Bake those beauties for about 20 minutes until cooked through.
Layering the Dish: While meatballs are baking, spread half of your pasta sauce evenly across the bottom of the greased baking dish. Layer half of the sub rolls over the sauce like soldiers ready for battle.
Add Meatballs and Cheese: Once baked, carefully place meatballs on top of sub rolls and pour remaining sauce over everything. Sprinkle shredded mozzarella generously on top—you want it cheesy!
Baking It All Together: Cover the dish with foil and bake in preheated oven for 25 minutes. Remove foil during the last 10 minutes to allow cheese to brown slightly.
Serving Time!: After baking, let it cool slightly before garnishing with freshly chopped basil if desired. Serve hot and watch everyone dive in like they’re at an all-you-can-eat buffet!
Now you’ve crafted something extraordinary—a comforting Meatball Sub Casserole that’s sure to impress friends and family alike! Enjoy every gooey bite!
You Must Know About Meatball Sub Casserole
- This showstopping Meatball Sub Casserole delivers restaurant-quality results using simple ingredients you probably already have at home
- The perfect balance of textures and flavors creates an unforgettable dining experience that will have everyone asking for seconds
- Picture-perfect presentation with vibrant colors makes this dish absolutely Instagram-worthy and guaranteed to impress any dinner guest
- Incredibly versatile recipe that works beautifully for weeknight dinners, meal prep, special occasions, or even outdoor entertaining sessions
Perfecting the Cooking Process
For perfect results, cook the meatballs first to get that golden brown crust, then prepare your sauce while they bake. Meanwhile, you can toast the bread to enhance flavor and texture. This sequence maximizes efficiency and ensures every component shines in your Meatball Sub Casserole.
Add Your Touch
Feel free to customize your Meatball Sub Casserole by swapping traditional beef meatballs for turkey or veggie alternatives. Experiment with different cheeses like provolone or pepper jack for a spicy kick. You can also add finely chopped veggies like bell peppers or spinach into the sauce for extra nutrition and color.
Storing & Reheating
To store leftovers, let the casserole cool completely before transferring it to an airtight container. It will keep well in the refrigerator for up to three days. When reheating, cover it with foil and warm it in a preheated oven at 350°F until heated through, ensuring the cheese remains melted and gooey.
Chef's Helpful Tips for Meatball Sub Casserole
- This professional-quality Meatball Sub Casserole relies on precise timing and temperature control to achieve restaurant-standard results consistently
- Master the art of mise en place by prepping all ingredients beforehand, ensuring smooth execution and preventing any last-minute cooking disasters
- The secret lies in layering flavors throughout the cooking process rather than seasoning only at the end for maximum depth
- Tip let the finished dish rest for optimal texture and flavor development before serving to hungry guests waiting eagerly
Sharing meals around my table is where I find joy; my friends rave about this casserole after a cozy movie night together, leaving me feeling like a culinary rockstar.
FAQ
What type of bread works best for a Meatball Sub Casserole?
A sturdy Italian hoagie roll or French baguette is ideal for holding up against saucy meatballs without getting soggy too quickly. Look for bread that has a crusty exterior but is soft inside; this will help maintain its structure while absorbing delicious flavors from the casserole.
Can I make Meatball Sub Casserole ahead of time?
Absolutely! Prepare the casserole up to the baking stage, cover it tightly, and refrigerate it overnight. When you’re ready to serve, just pop it in a preheated oven at 350°F until bubbly—perfect for stress-free entertaining on busy nights.
What are some great side dishes to serve with this casserole?
Serve your Meatball Sub Casserole alongside a fresh salad or garlic breadsticks for added crunch and flavor contrast! You could also pair it with roasted vegetables or potato wedges for a satisfying meal that covers all bases.
How do I know when my meatballs are fully cooked?
The best way to ensure they are cooked through is using an instant-read thermometer; aim for an internal temperature of 165°F. If you don’t have one handy, cut one open—the center should be no longer pink and juices should run clear.
Conclusion for Meatball Sub Casserole
In summary, making a delightful Meatball Sub Casserole is not just about combining ingredients—it’s about crafting an experience filled with flavors and textures that tantalize your taste buds. Remember to layer flavors thoughtfully, customize according to your preferences, and enjoy the process as much as the delicious outcome! This recipe is truly perfect for any occasion and guarantees smiles all around!

Meatball Sub Casserole
- Total Time: 1 hour
- Yield: Serves 8
Description
Meatball Sub Casserole is the ultimate comfort food, combining juicy meatballs, rich marinara sauce, and gooey melted cheese all nestled between crusty sub rolls. Perfect for cozy family dinners, game nights, or potlucks, this dish promises layers of flavor and satisfaction that will have everyone coming back for seconds. Easy to prepare and endlessly adaptable, it’s a recipe that guarantees smiles around the table.
Ingredients
- 1 lb ground beef (80/20)
- 1 tsp Italian seasoning
- 1 cup pasta sauce
- 2 cups shredded mozzarella cheese
- 4 sub sandwich rolls, cut in half
- ¼ cup grated Parmesan cheese
- Fresh basil for garnish (optional)
Instructions
- Preheat oven to 375°F (190°C) and grease a 9×13-inch baking dish.
- In a bowl, mix ground beef, Italian seasoning, breadcrumbs, egg, salt, and pepper by hand until well combined.
- Form mixture into golf ball-sized meatballs and place on a parchment-lined baking sheet. Bake for 20 minutes until cooked through.
- Spread half the pasta sauce on the bottom of the baking dish. Layer half of the sub rolls over the sauce.
- Place baked meatballs on top of the rolls and pour remaining sauce over them. Top generously with mozzarella cheese.
- Cover with foil and bake for 25 minutes. Remove foil during the last 10 minutes to brown the cheese.
- Let cool slightly before garnishing with basil and serving hot.
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Category: Main
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 piece (approx. 200g)
- Calories: 350
- Sugar: 4g
- Sodium: 820mg
- Fat: 18g
- Saturated Fat: 8g
- Unsaturated Fat: 9g
- Trans Fat: 0g
- Carbohydrates: 29g
- Fiber: 2g
- Protein: 18g
- Cholesterol: 60mg
Keywords: For added flavor, toast your sub rolls before layering them in the casserole. Substitute turkey or veggie meatballs for a lighter option or use different cheeses like provolone for variety.


